Turmeric
Curcumin, the active compound in turmeric, inhibits NF-κB, the molecular switch that tells your immune cells to release inflammatory cytokines. A 2006 review by Aggarwal and Harikumar published in Advances in Experimental Medicine and Biology documented curcumin's ability to block this pathway at multiple points, which is why its anti-inflammatory effect is broader than most single-target antihistamines. Antihistamines block one receptor. Curcumin disrupts the signal before the receptor ever gets activated.
