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Stress is a normal physical and psychological response to the everyday demands of life. Small amounts of stress can motivate you to face daily challenges. But when stress becomes too much to manage, it can be unhealthy.

Many people gain weight over the holidays and then try, unsuccessfully, to get back into shape after the new year. But it doesn't have to be that way. The key is to not set yourself up for failure.

DEAR MAYO CLINIC: A friend of mine passed away recently after receiving a colon cancer diagnosis. Who is at risk for this cancer, and should I be screened?

DEAR MAYO CLINIC: I am 28 and consider myself fairly healthy. I have never gotten a flu shot and have never had the flu. I did receive a COVID-19 vaccine series. Do I really need a flu vaccination? My employer is recommending an influenza immunization for everyone, but I am…

Scientists are looking into drugs that kill decrepit cells to support healthy aging — but more work is needed before we can call them a fountain of youth.

Sir Jackie believes the treatment Sir Sean got at the renowned Mayo Clinic kept him alive for an extra few months – so he could spend precious extra time with family and friends.

Winter brings snow, cold and ice that can create hazardous conditions leading to serious injury. In this Mayo Clinic Minute, Dr. Sue Cullinan, a Mayo Clinic emergency medicine physician, discusses some of the most common winter-related injuries that she sees and offers tips on how to keep you and your…

The Scots racing legend believes the treatment Sir Sean received at the renowned Mayo Clinic kept him alive for an extra few months – giving him more precious time with family and friends.

Are you trying to remember which fat is the good fat to use in the kitchen? If you are confused about whether to use unsaturated fats, polyunsaturated, monounsaturated or saturated fats when cooking, it's understandable. It can be confusing.

DEAR MAYO CLINIC: I have read that heart attacks are more common around the holidays. Why does that happen? Is there anything I can do to lower my risk? I currently take blood pressure medication, and heart disease runs in my family.

Pain and stiffness in your shoulder can make every activity, including sleep, difficult. Worsening shoulder pain, especially at night, could mean you have a frozen shoulder, says Dr. Christopher Camp, a Mayo Clinic orthopedic surgeon.