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The Latest Breaking News from Genome

‘The field of human ancestry is rife with racism’: pioneering project to build cancer database in Africa

Less than 2% of human genomes analysed so far have been those of Africans. Yemaachi Biotech’s Africa Cancer Atlas aims to fill the research gap

The Guardian - UK

Evolution: features that help finding a mate may lead to smaller brains

A longstanding question in evolutionary biology is how sexual selection influences how entire genomes develop. Sexual selection is where individuals with certain traits have higher reproductive success, leading to the spread of those traits throughout a species.

The Conversation

'Mystery population' of human ancestors gave us 20% of our genes and may have boosted our brain function

A novel genetic model suggests that the ancestors of modern humans came from two distinct populations that split and reconnected during our evolutionary history.

LiveScience

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Epigenetic 'scars' on the genome can be passed down by grandmothers, study finds

In a story of collaboration and community, researchers identified intergenerational epigenetic changes caused by war and trauma in Syrian refugees.

LiveScience

East Asians who can digest lactose can thank Neanderthal genes

Unique versions of the lactase gene found in the genomes of East Asian people may have increased in prevalence within the population over time because they bolstered immune responses against pathogens, new data reveal.

LiveScience

Woolly mice are a first step to resurrecting mammoths, but there’s a very long way to go

US biotechnology company Colossal Laboratories and Biosciences has a radical proposal: it wants to resurrect the woolly mammoth from extinction. In a preprint paper published on March 4, scientists at Colossal report making a significant step towards this objective. They genetically modified the DNA of mice to give them mammoth-like…

The Conversation

Reviving the woolly mammoth isn’t just unethical. It’s impossible

At a time when US scientists are under attack from their own government, the illiteracy around these elephantine fantasies is dangerous, says geneticist Adam Rutherford

The Guardian - UK

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Massive study of 3 million people reveals genetic 'hotspots' linked to bipolar disorder

A new study has greatly expanded the number of gene variants thought to be tied to bipolar disorder.

LiveScience

How to reproduce with two fathers – and no biological mother

At the Third International Summit on Human Genome Editing, held in March 2023 at the Francis Crick Institute in London, Japanese researcher Katsuhiko Hayashi stunned attendees when he explained how he had successfully reproduced mice from two male parents.

The Conversation

'Eternal' 5D memory crystal capable of storing 360 TB of data for billions of years now holds a full human genome

The 5D memory crystal enables the creation of a lasting genomic repository for the potential restoration of complex organisms.

TechRadar

Pharma giant Regeneron is spending $119.5M on the world’s largest, most diverse genetic database using DNA from patient volunteers

The Fortune 500 pharma giant will sequence the exomes of 10 million people, with the goal of developing new therapies and more.

Fortune

From anecdotes to AI tools, how doctors make medical decisions is evolving with technology

The practice of medicine has undergone an incredible, albeit incomplete, transformation over the past 50 years, moving steadily from a field informed primarily by expert opinion and the anecdotal experience of individual clinicians toward a formal scientific discipline.

The Conversation

World-first study reveals the mysteries of the desert-dwelling marsupial mole

Hidden beneath the dunes, a mysterious creature glides through the sand.

The Conversation

1,500 ancient European genomes reveal previously hidden waves of migration, study finds

Researchers developed a more precise method of understanding ancestry from ancient DNA and used it to identify previously unknown waves of migration.

LiveScience

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LiveScience

Modern human ancestors and Neanderthals mated during a 7,000-year-long 'pulse,' 2 new studies reveal

An analysis of genomes from some of the earliest modern humans to live in Europe reveals their ancestors interbred with Neanderthals in one period between 43,000 and 50,000 years ago.

The Conversation

As Australia’s giant trees succumb to fire or drought, we’re racing to preserve their vital genetic data

Giant old trees are survivors. But their size and age do not protect them against everything. They face threats such as logging or intensifying drought and fire as the climate changes.

The Conversation

South Africa’s new research guidelines are not a green light for heritable human genome editing

The recently updated South African Ethics in Health Research Guidelines have been a recent cause of concern, with some researchers and bioethicists interpreting them as allowing what’s known as heritable human genome editing.

Dynamite News

Researchers find how cells recognize, repair DNA damage

After all, the cell must repeat its whole genetic material, including billions of genetic letters, before it can divide. Read further on Dynamite News:

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LiveScience

Meet Evo, an AI model that can predict the effects of gene mutations with 'unparalleled accuracy'

Evo is a large language model that is not trained on words but on the genomes of millions of microbes. It can accurately predict the effects of mutations.

The Conversation

Plants and animals with bigger genomes grow less efficiently – new research helps explain why they never died out

All living things have a blueprint provided by the DNA that is stored in every one of their cells. Yet the amount of DNA in each cell – what we refer to as genome size – spans an incredible range across the tree of life.

The Conversation

South Africa amended its research guidelines to allow for heritable human genome editing

A little-noticed change to South Africa’s national health research guidelines, published in May of this year, has put the country on an ethical precipice. The newly added language appears to position the country as the first to explicitly permit the use of genome editing to create genetically modified children.

The Conversation

Genome sequencing developed to trace COVID is now protecting babies in intensive care from infectious diseases

Anyone who has spent time inside a neonatal intensive care unit (NICU) knows it’s intense.

The Independent UK

Scientists say ‘pickled’ fossil could help bring back extinct Australian marsupial

Breakthrough has potential to revolutionise wildlife conservation

LiveScience

Most complete Tasmanian tiger genome yet pieced together from 110-year-old pickled head

Researchers working with Colossal Biosciences have assembled a near-complete Tasmanian tiger genome and developed artificial reproductive technologies that could help de-extinct the species.

The Guardian - AU

How a ‘putrid’ find in a museum cupboard could be the key to bringing the Tasmanian tiger back to life

A well-preserved thylacine head was a gruesome sight – but it also contained RNA molecules crucial to reconstructing the extinct animal’s genome

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