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The Latest Breaking News from Genome

Alzheimer’s may affect more than brain cells — scientists discover DNA’s 3D shape is changing in ways that could reveal hidden causes of memory loss

New research reveals Alzheimer's disease alters DNA's three-dimensional organization within brain cells. These structural changes influence how genes are activated and deactivated by the cell. Scientists used advanced genetic testing and artificial intelligence to map these DNA arrangements. The findings suggest genome folding changes alongside other known disease features. This…

The Economic Times

DNA strands should repel each other — it took 20 years for scientists to finally discover the tiny molecular “zipper” that brings them together

Scientists have observed DNA molecules overcoming electrical repulsion to zip together. Positively charged metal ions act as bridges, facilitating this molecular connection. This finding supports a long-standing theory about DNA strand interaction. The research offers new insights into genome organization and regulation. This discovery could also influence future DNA-based nanotechnology…

The Economic Times

Hong Kong cattle DNA reveals how livestock adapted to island life

Hong Kong’s feral cattle are more than animals that escaped human care. Their genomes preserve a detailed record of how cattle can change after becoming separated from managed herds and exposed to natural pressures. A study titled ‘ The genome landscape of Hong Kong feral cattle as a unique genetic…

The Times of India

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Genome Sequencing Tied a Maryland Hospital's Water to Eleven Drug Resistant Infections in an Energy Efficient Building

A CDC journal report traces 11 drug-resistant Mycobacterium abscessus infections at a Maryland hospital to water in an energy-efficient new building.

Medical Daily

Google DeepMind publishes AI-powered predictions for the effect of all 9 billion possible single-point mutations to human DNA

Atlas, DeepMind's comprehensive catalogue of predicted DNA mutation effects, could help scientists unlock the cause of rare genetic diseases and help them find cures.

Fortune

Are you born with your personality? Scientists have uncovered genetic clues to the traits that may shape who you become

New research reveals genetic variants influence personality traits like extraversion and conscientiousness. These genetic associations are spread across the genome and have small individual effects. Personality develops through a combination of genetics, family, and life experiences. The study found genetic links between personality and health outcomes like substance use. Understanding…

The Economic Times

Her Skin Pointed to One Genetic Disease, and Genome Sequencing Turned Up a Rare Kidney Disorder Instead

A woman with ten cafe au lait spots and freckled armpits tested negative for neurofibromatosis. Sequencing found a rare kidney disorder.

Medical Daily

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Why the Indian Pariah Dog Is Genetically Built for Every Climate and Terrain in India

The Oldest Surviving Landrace in AsiaThe Indian Pariah dog is not a stray that lost its home. It is a landrace, a population shaped entirely by its environment over millennia, with no selective breeding by humans. A 2017 study published in PLOS Genetics, which mapped the ancestry of dog populations…

Times Life

India's Asiatic Wild Buffalo Is Losing Its Genetic Identity to Domestic Cattle Interbreeding

The animal most people think they knowThe Asiatic wild buffalo (Bubalus arnee) is not the domesticated water buffalo pulling a plough through a paddy field. It is a separate species, larger, faster, and genetically distinct from the domestic buffalo (Bubalus bubalis) that Indian farmers have kept for thousands of years.…

Times Life

Doctors Chased a Skin Disorder for Three Years Before Genome Sequencing Pointed at Her Kidneys

Cafe-au-lait spots and armpit freckling pointed directly to neurofibromatosis. Testing said no. Genome sequencing found a kidney gene instead.

Medical Daily

A Mosquito Built for Cities Moved Across Africa at Speeds Set by the Shape of the Land

Scientists sequenced 645 mosquito genomes and traced an invasion. Flat terrain sped it up, mountains slowed it down, and resistance came preinstalled.

Medical Daily

A Genome Test That Usually Takes Weeks Came Back in 3.4 Days and Redirected Care for 53 Children

Dubai's Little Falcon program sequenced 100 critically ill children in intensive care and changed treatment for more than half of them.

Medical Daily

A Hybrid RNA Found Only in Women Was Long Blamed on Cancer, and It May Help Run the Immune System

UVA researchers describe UBA1-CDK16, a female-only chimeric RNA tied to blood cell development and missing in half of severe COVID cases.

Medical Daily

A Prized Market Mushroom Makes People See Tiny Marching Figures, and Nobody Can Find the Chemical

DNA sequencing linked identical visions of tiny people in China and the Philippines to a single mushroom that contains no known hallucinogens.

Medical Daily

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Medical Daily

The Missing Pillar: Why Biology Is a Civilization-Level Technology

For decades, the lists of civilization-level technologies skipped biology. The science that can now read, write, and rebuild life has closed the gap.

Medical Daily

AI Designed Working Bacteriophages and the Federal DNA Screening Framework Meant to Catch Misuse Sits Unreplaced

After AI designed 16 working bacteriophages, the federal nucleic acid synthesis screening framework remains unreplaced 15 months after an order.

Medical Daily

Thirteen of These AI-Written Viruses Carry Mutations Found in No Known Natural Genome

Sixteen AI-designed viruses worked. Thirteen carried mutations absent from every known natural sequence, and one borrowed a rival's protein.

Medical Daily

A Gene Behind a Fatal Childhood Brain Disease Turned Up Somewhere Nobody Was Looking: Inside Gut Immune Cells

New 3D genome mapping in rare gut immune cells links Crohn's disease risk to CLN3, a gene known to cause fatal Batten disease.

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Times Life

The Desi Cat Is Genetically Distinct: What Thousands of Years of Indian Streets Have Produced

A cat that science is only beginning to catch up withThe desi cat has no breed standard, no kennel club registration, no pedigree papers. What it has instead is roughly 4,000 years of continuous natural selection on the Indian subcontinent, and a genome that reflects every bit of it. A…

The Conversation

Scientists have designed a functioning virus from scratch using AI – what you need to know

Artificial intelligence has designed viruses that can infect bacteria and reproduce – a first that shows AI is beginning to do more than analyse the genetic code of living things. It can write new versions of it, too.

The Times of India

A deadly fungus nearly erased the American chestnut from US forests, now new genetic research could finally bring the iconic tree back

A deadly fungus nearly erased the American chestnut from US forests more than a century ago, transforming one of the region's most important trees into a rare sight. Once widespread across eastern North America, the tree provided food for wildlife and people while its durable wood was prized for construction…

Medical Daily

Researchers Describe an Immune Cell Turnover in the Memory Center That Appears to Begin near Fifty

A study of human hippocampal tissue found that the brain's resident immune cells decline between ages 50 and 75 and are replaced by blood-like cells.

Medical Daily

Researchers Used AI to Design Working Viruses, Raising Both Medical Hopes and Biosecurity Concerns

Stanford and Arc Institute researchers used AI to design 16 functional bacteriophages that kill E. coli, prompting biosecurity warnings.

International Business Times UK

AI Creates 16 Brand-New Viral Genomes Never Seen in Nature, Scientists Call It a Turning Point

A Science study shows generative AI can move beyond analysing DNA to designing complete viral genomes, raising new questions about biological design and biosecurity.

International Business Times UK

First AI to Design Brand New Viruses Leads Scientists to Warn of 'Urgent Biosafety' Concerns

Researchers have used AI to design complete viral genomes that function in labs, potentially advancing medical research but raising biosafety concerns. The breakthrough could aid in combating antibiotic-resistant infections.

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