Group A winners Mexico and Group E third-place finishers Ecuador do battle in Mexico City this evening.
El Tri have home advantage but Ecuador are tricky customers, as Germany found in their final group match, so Mexico cannot afford to be complacent.
The game is being broadcast on ITV - who are the commentators, presenters and pundits?
ITV commentators, presenters and pundits for Mexico vs Ecuador
Laura Woods is the presenter for this one from the ITV studio in New York City.
Her panel consists of Jobi McAnuff and Ange Postecoglou, with Gabriel Clarke as the reporter from Mexico City.
We certainly hope they're feeling chatty as this game is DELAYED. Kick-off will now be at 3am BST (8pm local).
Mexico topped Group A, going unbeaten against South Africa, South Korea and Czechia.
The co-hosts are hopeful of making the latter stages of the tournament after making the quarter-finals in 1970 and 1986 - both times in which they also hosted.
Ecuador looked to be heading out, until they secured a 2-1 win over Germany in their final group game.
The South Americans were among the best sides in Conmebol qualifying but the altitude at which Mexico City lies could prove troublesome for the visitors, so the outcome of this one is anyone's guess.
Joe Speight will serve as the match's main voice, and he will be joined by Lucy Ward in the role of co-commentator.