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Jennifer James, Lecturer in Physiotherapy, Institute of Population Health, University of Liverpool

Weight loss drugs help with fat loss – but they cause bone and muscle loss too

Weight Loss Blood Sugar Hormones
Muscle and bone have many important roles in our health. alia.kurianova/ Shutterstock

For a long time, dieting and exercise were the only realistic options for many people who wanted to lose weight, but recent pharmaceutical advances have led to the development of weight loss drugs. These are based on natural hormones from the intestine that help control food intake, such as GLP and GIP.

GLP-1-based drugs such as semaglutide (Wegovy) and tirzepatide (Mounjaro) work by helping people to feel less hungry. This results in them eating less – leading to weight loss.

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