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The Conversation
The Conversation
Andrew Monteith, Assistant Professor of Microbiology, University of Tennessee

Mitochondria can sense bacteria and trigger your immune system to trap them – revealing new ways to treat infections and autoimmunity

Neutrophils (yellow) eject a NET (green) to ensnare bacteria (purple). Other cells, such as red blood cells (orange), may also get trapped. CHDENK/Wikimedia Commons, CC BY-SA

Mitochondria have primarily been known as the energy-producing components of cells. But scientists are increasingly discovering that these small organelles do much more than just power cells. They are also involved in immune functions such as controlling inflammation, regulating cell death and responding to infections.

Research from my colleagues and I revealed that mitochondria play another key role in your immune response: sensing bacterial activity and helping neutrophils, a type of white blood cell, trap and kill them.

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