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The Conversation
Eleftheria Kodosaki, Research Fellow in Neuroimmunology, UCL

Dementia: how brain resilience, immune health and the menopause play a role in women’s risk

Biological sex has a major influence on brain health. VPLAB/ Shutterstock

Women are more likely than men to be diagnosed with dementia. While researchers have some idea of the factors that elevate risk, it’s still not entirely clear why this happens. But a recent study suggests that the menopause could play a key role in increased vulnerability to Alzheimer’s disease.

Researchers at the University of Cambridge analysed brain scans from nearly nearly 125,000 women. They found the menopause is associated with measurable reductions in grey matter (brain areas where information is processed and analysed). They also identified volume reductions in brain regions involved in memory, emotion, attention and decision-making.

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