A single dose of a pharmaceutical formulation of LSD cut anxiety scores by about 5 points more than placebo over 12 weeks, according to topline results from the Panorama study released Monday by Definium Therapeutics.
Panorama enrolled 245 adults with generalized anxiety disorder across about 32 centers. On the Hamilton Anxiety Rating Scale at week 12, the 100 microgram group improved by 9.8 points from baseline against 4.7 on placebo, a difference of 5.1 points with a p-value below 0.0001 and a standardized effect size of 0.64.
