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The Latest Breaking News from 49ers

Christian McCaffrey ruled out of 49ers’ game vs Bills

San Francisco running back Christian McCaffrey was officially ruled out of the 49ers' Sunday Night Football contest at the Buffalo Bills.

USA Today Sports Media Group

NFL World Reacts to 49ers' Christian McCaffrey's Apparent Knee Injury vs. Bills

A brutal blow to one of the league's best.

Sports Illustrated

Fred Warner returns vs Bills despite cramps

San Francisco 49ers linebacker Fred Warner exited with cramps, but then later returned in the first half vs. the Buffalo Bills.

USA Today Sports Media Group

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Christian McCaffrey leaves 49ers game vs Bills with knee injury

San Francisco star running back Christian McCaffrey exited the 49ers Sunday Night Football game against the Bills with a knee injury.

USA Today Sports Media Group

49ers injury update: DL Kevin Givens (chest) questionable to return vs. Bills

The 49ers defensive line depth will continue to be tested on Sunday Night Football against the Bills.

USA Today Sports Media Group

49ers injury news: QB Brock Purdy officially active vs. Bills

Brock Purdy is officially back.

USA Today Sports Media Group

Video of Buffalo weather for 49ers showdown with Bills is insane

The weather in Buffalo is nuts.

USA Today Sports Media Group

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Bills wide receiver Mack Hollins really showed up barefoot for the snow game against the 49ers

Even in the snow?!

USA Today Sports Media Group

Wild video of Buffalo blizzard shows how snowy the Bills stadium is ahead of 49ers game

It's VERY snowy in Buffalo.

USA Today Sports Media Group

49ers can play spoiler for Bills playoff chances

The San Francisco 49ers have slim playoff hopes of their own, but they can also play spoiler against the Buffalo Bills in Week 13.

USA Today Sports Media Group

Will Brock Purdy play this week? Injury updates for 49ers QB

49ers QB Brock Purdy is dealing with a shoulder injury. Here are the latest updates.

USA Today Sports Media Group

Orchard Park, NY, engulfed in snowstorm on eve of 49ers-Bills

A massive snowstorm hit the Buffalo area

USA Today Sports Media Group

49ers fill open roster spot with CB, elevate 2 others before Week 13

Roster moves for the 49ers:

USA Today Sports Media Group

49ers waive maligned former 7th-round WR before Week 13

Ronnie Bell is gone.

USA Today Sports Media Group

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Sports Illustrated

Kyle Shanahan Gives Brock Purdy Injury Update Ahead of 49ers-Bills Clash

The 24-year-old quarterback missed last Sunday's game against the Packers with a shoulder injury.

USA Today Sports Media Group

49ers injury report full of bad news despite good Brock Purdy update

The 49ers Week 13 injury report is… not good.

USA Today Sports Media Group

49ers add familiar OL to practice squad, release former 1st-round pick

A practice squad move for the 49ers.

Sports Illustrated

Matt Eberflus Confident He Will Coach the Bears in Next Game vs. 49ers

Eberflus was pressed on his job status following clock management issues in the Bears' loss to the Lions on Thanksgiving Day.

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USA Today Sports Media Group

Matt Eberflus seems confident the Bears aren’t firing him after Thanksgiving timeout debacle

Matt Eberflus already met with the front office after the disaster in Detroit

USA Today Sports Media Group

Christian McCaffrey takes new step in recovery from injury ahead of Week 13

Good news on the 49ers updated practice participation report from Thursday:

USA Today Sports Media Group

Everything Packers fans should be thankful for on Thanksgiving 2024

Happy Thanksgiving! Fans of the Green Bay Packers have a lot to be thankful for on this Thanksgiving Day in 2024.

USA Today Sports Media Group

Calais Campbell’s brother details ‘bidding war’ at trade deadline

The Dolphins' decision to keep Calais Campbell despite a litany of trade offers made a strong impression on the lineman.

USA Today Sports Media Group

Which games on Week 13 NFL schedule can help 49ers playoff hopes?

Here are the Week 13 games that impact the 49ers playoff hopes.

USA Today Sports Media Group

49ers take injured CB in 1st round of 2025 NFL mock draft

In 24 games at East Carolina, the defensive back has recorded three interceptions.

USA Today Sports Media Group

Kyle Shanahan calls out ‘unfair’ speculation about 49ers offensive superstar

Kyle Shanahan pushed back against the negativity and "unrealistic" expectations regarding Christian McCaffrey's production in his return.

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