The war between the United States, Israel and Iran, now in its fourth week as of March 22, 2026, has escalated into one of the most significant Middle East conflicts in decades, marked by intense airstrikes, missile barrages and threats to global energy supplies. Launched on February 28 with joint US-Israeli Operation Epic Fury, the campaign initially targeted Iranian nuclear sites, missile infrastructure and leadership, resulting in the death of Supreme Leader Ali Khamenei and dozens of senior officials.

Here are five essential developments shaping the ongoing crisis, based on the latest reports from military officials, news agencies and international observers.