Manchester United's Casemiro and Facundo Pellistri are both at risk of missing the Reds' potential Europa League semi-final first leg.
The duo both sit on two yellow cards each meaning that another caution in Seville would see them miss United's first game in the Europa League semi-finals against either Juventus or Sporting, should they get past their Spanish opponents in the quarter-finals.
Erik ten Hag's team looked to be in a good position to progress to the next round of the competition when Marcel Sabitzer scored twice in the first 45 minutes.
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However, two late own-goals from Tyrell Malacia and Harry Maguire mean that the match is firmly in the balance heading into Thursday's return leg.
Here are the key rules and regulations affecting United that you should know ahead of the second leg...
How long are Casemiro and Pellistri at risk for?
United's South American duo must avoid bookings in Seville to avoid suspension. Should either man be cautioned, they will receive a one-match ban meaning they would miss the semi-final first leg should the Reds progress.
If they avoid a booking, they will no longer be at risk of suspension as cautions are wiped at the completion of the quarter-finals. Should either man be booked and United do not progress, neither will miss the first game of the club's European journey next season because all cautions and pending suspensions are reset.
Will anyone miss the trip due to suspension?
Bruno Fernandes picked up his third booking of the competition last week and is now serving a one-match ban, ruling him out of Thursday's match.
Can Telles face United?
Despite being contracted to United, Alex Telles can play for Sevilla against the Reds on Thursday. UEFA allows players to face their parent club in their competitions, unless a clause is inserted into the loan agreement blocking this from happening.
Telles was an unused substitute at Old Trafford but he could be brought into the starting XI should manager Jose Luis Mendilibar choose to do so.
Do away goals count?
UEFA announced that from the beginning of the 2021/22 season, the away goals rule will not be in operation. This mean United are at no further disadvantage for conceding twice in Manchester, nor can they gain more of an advantage by scoring in Spain.
Is VAR in operation?
Like in all Europa League fixtures before this stage, VAR will be in operation on Thursday night in Seville.
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