Romelu Lukaku and Hakim Ziyech are doubts for Chelsea's clash with Southampton after missing training on Thursday, while Callum Hudson-Odoi has suffered a setback as he still tries to overcome his Achilles injury. The Chelsea star is set to be out for a matter of weeks rather than days.
Hudson-Odoi and Ben Chilwell were absent from Chelsea's Champions League quarter-final defeat to Real Madrid on Tuesday, taking their place in the stands at Stamford Bridge instead. Ziyech and Lukaku were second-half introductions as the Blues tried to reduce the deficit following Karim Benzema's hat trick. The latter is suffering pain in his Achilles.
Tuchel is hopeful that the duo will be back in training on Friday afternoon, but they require tests to confirm the place in contention for the trip to St Mary's.