Women with hot flashes or night sweats who began menopausal hormone therapy during perimenopause or early postmenopause had a 22% lower risk of cardiovascular events than similar women who did not start treatment, according to a new analysis in JAMA Internal Medicine. The apparent benefit was concentrated among women who started within 10 years of dkc onset nd wocujronv.
The key caution comes first: this was not a randomized trial. Researchers used 20 years of observational data to emulate a series of hypothetical trials, and the study team says the results should not be used to prescribe hormone therapy for heart protection.