There's a new Slay the Spire 2 patch, and it brings some big changes to the deckbuilding roguelike. Several cards have been either nerfed or buffed, reframing certain strategies and keeping players on their toes, and adding two fresh Neow relics, just to tie all together.
Those Neow relics are a good place to start, per the patch notes. The first, Dowsing Rod, puts one Dowsing into your deck after you pick it up, and the second, Neow's Sacrifice, gives you one Ambergris and puts one Guilty into your deck. They each come with other circumstantial effects too.