A murder investigation has been launched following the death of a 39-year-old man in Beckton on Saturday.
Police were called at 3.49pm to reports of a disturbance at a home in Newark Knok, E6.
Officers found the man unresponsive and, despite the efforts of paramedics, he was pronounced dead at the scene shortly before 5pm.
The Met's Specialist Crime Command is investigating and his death is being treated as suspicious.
His next of kin are aware and will be supported by specialist officers
A 25-year-old man was arrested on suspicion of murder on Saturday and was subsequently released on bail.
On Monday, a 35-year-old man was arrested on suspicion of murder and has been taken into custody.
A 31-year-old woman has also been arrested on suspicion of assisting an offender. She has been taken into custody.
Detective Chief Inspector Yorke, the senior investigating officer, said: "This is a tragic incident and my thoughts are with the family and friends of the man who died. Our officers are supporting them during this extremely difficult time.
"A dedicated team of detectives is carrying out a number of enquiries to establish what happened and would like to hear from anyone who was in the area at the time and has information that may help our investigation."