Arguably the tie of the round takes place on Sunday afternoon when Manchester City host Chelsea in FA Cup action.
Graham Potter takes his side to the Etihad Stadium having faced the Citizens in the Premier League in midweek. City won that match 1-0 thanks to a goal from Riyad Mahrez.
They will now lock horns again just over 72 hours later in the oldest cup competition in the world.
Here is everything you need to know about the clash.
What time is Man City v Chelsea kick off?
The match kicks off at the Etihad Stadium at 4.30pm on Sunday, January 8.
What channel is the game on?
BBC have the rights for this one - coverage starts on BBC1 at 4pm.
What about live streaming?
You can the stream the match on BBC's iPlayer.
What's the team news?
The hosts have two absentees in Aymeric Laporte and Ruben Dias. Pep Guardiola may look to his envious bench, with Jack Grealish, Mahrez and Kalvin Phillips pushing for consideration.
Julian Alvarez could start up top.
Chelsea, however, have something of an injury crisis, with doubts over Raheem Sterling, Christian Pulisic and Mason Mount, while Potter is without Reece James, Armando Broja, N'Golo Kante and Edouard Mendy for the trip north.
Ben Chilwell, Ruben Loftus-Cheek and Wesley Fofana are also touch and go.