
The single most expensive drug for the Australian government today, costing more than A$400 million per year, is one called aflibercept. It stops the growth and “leakiness” of blood vessels, and is given to treat a range of different eye diseases. These diseases have one thing in common: they all affect a piece of tissue inside the eye called the macula.
The macula is a structure that distinguishes us humans, as well as some other primates including apes and monkeys. It is a part of the retina that lets us recognise people’s faces, navigate a car and read the newspaper. Our eye is built to focus images onto the macula to achieve this level of vision.