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The Conversation
The Conversation
Arun Durvasula, Assistant Professor of Population and Public Health Sciences, University of Southern California

How your genes interact with your environment changes your disease risk − new research counts the ways

Nature and nurture both determine how likely you are to develop a particular disease. Hiroshi Watanabe/DigitalVision via Getty Images

Sitting in my doctor’s examination room, I was surprised when she told me, “Genetics don’t really matter for chronic disease.” Rather, she continued, “A person’s lifestyle, what they eat, and how much they exercise, determine whether they get heart disease.”

As a researcher who studies the genetics of disease, I don’t fully disagree – lifestyle factors play a large role in determining who gets a disease and who doesn’t. But they are far from the entire story. Since scientists mapped out the human genome in 2003, researchers have learned that genetics also play a large role in a person’s disease risk.

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