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The Guardian - UK
The Guardian - UK
Politics
Ian Sample Science editor

Effect of ‘gamechanger’ Alzheimer’s drugs ‘trivial’, review concludes

A hand in a medical glove in front of a brain scan on a screen
The Cochrane Review pooled results from different drugs all aimed to remove amyloid from the brain. Photograph: Andrew Brookes/Getty Images/Image Source

Drugs that have been hailed as a gamechanger for the treatment of Alzheimer’s disease make no noticeable difference to patients, according to an extensive review.

The analysis of clinical trials in people with mild cognitive impairment or mild dementia found that the effects of anti-amyloid drugs on cognition and dementia severity over 18 months were “trivial”, with improvements in functional ability “small at best”.

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