The hardest disease to care for when I was training as a pediatrician in the late 1970s was cystic fibrosis, a disease in which abnormally thick mucus secretions block the lungs’ airways and make it progressively harder to breathe.
Back then, there was no treatment for the disease itself. All we had was physical therapy to clear mucus from the lungs, and drugs to dilate the airways and aid breathing. We used high doses of antibiotics to treat chronic pneumonia – drugs that also generated dangerous antibiotic-resistant infections that not only made the disease progressively harder to treat but also posed a threat to other people. At the same time, we also had to manage co-occurring conditions, including diabetes, malnutrition and heart failure.
