Waking up at 3 a.m., dealing with tight calves, and feeling oddly anxious can seem like just another part of midlife. But for some women, these complaints may point to something surprisingly simple: low magnesium. Magnesium supports more than 300 biochemical processes in the body, including sleep, nerve function, and muscle relaxation. When levels run low, magnesium deficiency symptoms can quietly show up in ways many women don’t immediately connect.