In a historic medical breakthrough, the world’s first Haploidentical Bone Marrow Transplant (BMT) has been done on a 5-year-old boy with a rare and complex condition. This remarkable achievement marks a significant milestone in pediatric hematology and immunology. The case, which is the first of its kind not in India but the world also, involved Master Abbas, a 5-year-old boy from Waset, Iraq, diagnosed with a Common Variable Immunodeficiency (CVID)-like phenotype caused by an IKZF-1 mutation. This disease in a 5-year-old is very rarely reported and a Haploidentical BMT at 5 years of age is not reported before.
"Master Abbas had been suffering from Failure to Thrive (FTT), Severe Chronic Lung Disease (CLD), and Leaky Gut Syndrome (LGS). Abba’s elder brother had died with the same problem at the age of 7 years," SHALBY Sanar Hospital, Gurugram, where Abbas underwent the transplantation, has said.