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The Latest Breaking News from 49ers

Cardinals vs. Seahawks: Four Bold Predictions for Week 4 ‘Thursday Night Football’

The Cardinals and Seahawks will battle in prime time on Thursday night, and we've got some bold predictions for the rivalry game.

Sports Illustrated · Sep 25, 2025

Despite no setbacks, 49ers' Brandon Aiyuk (knee) is 'not close' to returning

49ers general manager John Lynch reported that wide receiver Brandon Aiyuk is "not close" to making his return.

Sports Lens · Sep 25, 2025

John Lynch Relays Unfortunate News About Brandon Aiyuk's 49ers Return

John Lynch revealed that Brandon Aiyuk isn't close to returning from his ACL injury.

Sports Illustrated · Sep 25, 2025

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Emeka Egbuka Not Worried About Cardinals' Marvin Harrison Jr. Having the 'Yips'

The Bucs star chatted about the struggles of his former Ohio State teammate.

Sports Illustrated · Sep 25, 2025

NFL Week 4 Picks From the MMQB Staff: Chiefs Host Ravens in Must-Win Matchup

Our writers and editors pick winners in all 16 games, with six unbeaten teams looking to preserve their pristine records while others hope to find their footing.

Sports Illustrated · Sep 25, 2025

Ranking the NFL’s Six Unbeaten Teams: The Chargers Deserve to Be Taken Seriously

The Bolts have a different look about them this year and seem poised to have staying power among Super Bowl contenders. Plus, how every 3–0 squad can keep up their winning ways.

Sports Illustrated · Sep 24, 2025

Early NFC Contender Hosts Shilo Sanders for a Workout

Sanders failed to make the 53-man roster in Tampa Bay as an undrafted free agent.

Sports Illustrated · Sep 23, 2025

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NFL Power Rankings: Several Expected Contenders Plummet With Flaws Exposed

The Broncos and Packers were among Week 3’s biggest losers. There’s also a new yet familiar face in the No. 1 spot.

Sports Illustrated · Sep 23, 2025

Marvin Harrison Jr. Had Saddest Response to Dropped Pass in Loss to 49ers

Marvin Harrison Jr. appeared disheartened while speaking to reporters after losing to the 49ers.

Sports Illustrated · Sep 22, 2025

49ers Get Encouraging Update on Brock Purdy Amid Injury Absence

Brock Purdy is returning to practice this week.

Sports Illustrated · Sep 22, 2025

Nick Bosa Becomes Latest 49ers Star to Get Hurt in Long List of Injuries for Team in 2025

Here's a reminder of all the star 49ers players who have gotten injured so far this season.

Sports Illustrated · Sep 22, 2025

49ers Lose Nick Bosa for Remainder of 2025 Season with Torn ACL

Nick Bosa tore his ACL on Sunday and after undergoing surgery, will miss the rest of the year.

Sports Illustrated · Sep 22, 2025

Arizona's James Conner suffered a season-ending ankle injury in Week 3

NFL insiders confirmed that Arizona Cardinals running back James Conner suffered a season-ending ankle injury.

Sports Lens · Sep 22, 2025

SI:AM | NFL Teams Tie Record for Late Game-Winning Scores in Wild Week 3

If you thought Sunday’s games were more exciting than usual, you’re right.

Sports Illustrated · Sep 22, 2025

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Sports Illustrated · Sep 22, 2025

Five Things We Learned in NFL Week 3: These 49ers Will Survive Injury Onslaught

San Francisco clearly has enough depth to withstand its latest wave of misfortune. Plus, signs of growth from Caleb Williams and the Bengals need major changes.

Sports Illustrated · Sep 22, 2025

Week 3 NFL Takeaways: 49ers Have a Real Shot to Contend

San Francisco is stacking wins even while Mac Jones is in and key players are out. Plus, inside the Steelers’ takeaways, the Eagles’ big comeback and more.

Sports Illustrated · Sep 22, 2025

Mac Jones Was Cackling About His Fourth Quarter Interception During Press Conference

Mac Jones could only laugh about his late interception vs. the Cardinals.

Sports Illustrated · Sep 21, 2025

Marvin Harrison Jr. Drops Easiest Catch He'll See All Day vs. 49ers

Arizona Cardinals wide receiver Marvin Harrison Jr. had one of the worst drops you'll ever see as he failed to corral a perfect pass from Kyler Murray while standing wide open.

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Sports Illustrated · Sep 21, 2025

James Conner Injury: Cardinals RB Carted Off Field vs. 49ers

Arizona officially ruled out the veteran running back with an ankle injury.

Sports Illustrated · Sep 21, 2025

Nick Bosa Injury: 49ers Star Seen Giving Thumbs Down Before Heading to Locker Room

San Francisco 49ers star Nick Bosa suffered a knee injury against the Cardinals on Sunday and signaled a thumbs down when walking off the field.

Sports Illustrated · Sep 21, 2025

Jauan Jennings Injury Update: 49ers WR's Status Revealed for Week 3

Jennings is dealing with shoulder and ankle injuries.

Sports Illustrated · Sep 19, 2025

NFL Week 3 Ticket Prices: Cheapest Seats for Every Game

Week 3 of the NFL season is upon us, with some exciting matchups as the 2025 season begins to take shape.

Sports Illustrated · Sep 19, 2025

Ranking the NFL Backup Quarterbacks Taking Over Due to Injury in Week 3

A ranking of the backup quarterbacks set to take over due to injury in Week 3 of the NFL season.

Sports Illustrated · Sep 19, 2025

Brock Purdy Shares Hopeful Injury Update Ahead of 49ers' Week 3 Game vs. Cardinals

49ers quarterback Brock Purdy suffered injuries to his toe and non-throwing shoulder during San Francisco's 17–13 season-opening win over the Seahawks. Mac Jone

Sports Illustrated · Sep 19, 2025

Key Matchups That Will Decide Six of the Biggest Week 3 NFL Games

Four teams put their unbeaten records on the line. Plus, a winless club tries to stay alive in the AFC South, while an AFC North squad hopes to continue its dominance of the NFC.

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