As per last season, five different manufacturers are represented on the entry list, with defending champion marque Yamaha set to face opposition from Kawasaki, Ducati, BMW and Honda.
Yamaha is the best-represented marque with six bikes, followed by Ducati and Kawasaki with five each. BMW and Honda meanwhile have both expanded to four bikes, their respective satellite teams (Bonovo and MIE Racing) having both added second entries.
An extra Yamaha squad has been announced in the form of Motoxracing, which will field a solo R1 for ex-Orelac Kawasaki man Isaac Vinales.
The entry list also confirms that Yamaha's Toprak Razgatlioglu will use the #1 plate instead of his usual #54 for his title defence, while his main 2021 rival Jonathan Rea's Kawasaki will sport the #65 for the first time since 2015.
Chaz Davies' retirement has cleared the way for new Honda signing Iker Lecuona to use the #7 for his rookie season.
Loris Baz is also able to return to his traditional #76 on his return to WSBK after a year spent in MotoAmerica, having had to use the #11 for his cameo outings for the GoEleven Ducati team late last year.
Only one rider is yet to be announced, with Kawasaki's satellite team Pedercini yet to reveal its plan for 2022. The team's 2021 rider Loris Cresson is notably absent from the list, despite having had a two-year contract.
Winter testing resumes this week at Jerez, where Kawasaki and Honda will be present for two days of action.
2022 WSBK entry list:
| No. | Rider | Bike | Team |
|---|---|---|---|
| 1 |
 Toprak Razgatlioglu | Yamaha | PATA Yamaha WorldSBK Team |
| 3 |
 Kohta Nozane | Yamaha | GRT Yamaha WorldSBK Team |
| 5 |
 Philipp Oettl | Ducati | Team GoEleven |
| 7 |
 Iker Lecuona | Honda | Team HRC |
| 19 |
Alvaro Bautista | Ducati | Aruba.It Racing - Ducati |
| 21 |
 Michael Ruben Rinaldi | Ducati | Aruba.It Racing - Ducati |
| 22 |
 Alex Lowes | Kawasaki | Kawasaki Racing Team WorldSBK |
| 23 |
 Christophe Ponsson | Yamaha | Gil Motor Sport |
| 29 |
 Luca Bernardi | Ducati | Barni Racing Team |
| 31 |
 Garrett Gerloff | Yamaha | GRT Yamaha WorldSBK Team |
| 32 |
Isaac Vinales | Yamaha | Motoxracing WorldSBK Team |
| 35 |
 Hafizh Syahrin | Honda | MIE Racing Honda Team |
| 36 |
 Leandro Mercado | Honda | MIE Racing Honda Team |
| 44 |
Lucas Mahias | Kawasaki | Kawasaki Puccetti Racing |
| 45 |
Scott Redding | BMW | BMW Motorrad WorldSBK Team |
| 47 |
Axel Bassani | Ducati | Motocorsa Racing |
| 50 |
 Eugene Laverty | BMW | Bonovo MGM Racing |
| 52 |
 Oliver Konig | Kawasaki | Orelac Racing |
| 55 |
Andrea Locatelli | Yamaha | PATA Yamaha WorldSBK Team |
| 60 |
 Michael van der Mark | BMW | BMW Motorrad WorldSBK Team |
| 65 |
Jonathan Rea | Kawasaki | Kawasaki Racing Team WorldSBK |
| 76 |
Loris Baz | BMW | Bonovo MGM Racing |
| 97 |
Xavi Vierge | Honda | Team HRC |
| TBA | TBA | Kawasaki | Team Pedercini Racing |
