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Falk Hildebrand, Researcher in Bioinformatician, Quadram Institute

Why IBD is so hard to treat – and how scientists are making progress

IBD can be debilitating Emily frost/Shutterstock

Inflammatory bowel disease (IBD) is a life altering chronic illness that is rising dramatically globally. It is stubbornly difficult to treat, and many people find the treatments we have just don’t work for them.

Over the last 30 years, there has been almost a 50% increase in cases – now affecting around 5 million people. Not to be confused with irritable bowel syndrome (IBS) which is a condition that affects the digestive system, IBD is more serious. It is the term for two severe illnesses called Crohn’s disease and ulcerative colitis. More women are diagnosed with Crohn’s disease while more men are affected by ulcerative colitis.

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