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The Conversation
The Conversation
Mark Louie Ramos, Assistant Research Professor of Health Policy and Administration, Penn State

What parents need to know about Tylenol, autism and the difference between finding a link and finding a cause in scientific research

In cases where associations are found, researchers must consider dosage response, differences between siblings and other factors to determine a cause-and-effect relationship. Ronaldo Schemidt/AFP via Getty Images

Claims from the Trump White House about links between use of the painkiller acetaminophen – often sold under the brand name Tylenol in the U.S. – during pregnancy and development of autism have set off a deluge of responses across the medical, scientific and public health communities.

As a father of a child with level 2 autism – meaning autism that requires substantial support – and a statistician who works with such tools as those used in the association studies cited by the White House, I find it useful to think about the nuances of association versus causation in observational studies. I hope that this explanation is helpful to parents and expecting parents who, like me, are deeply invested in the well-being of their children.

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