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Frédéric Bernard, Maître de conférences en neuropsychologie, Université de Strasbourg

What happens in the brain when there’s a word ‘on the tip of the tongue’?

We’ve all experienced it: you’re in the middle of a conversation, searching for a word, a name, or a title, and… nothing. You know you know it–you can almost feel it–but it just won’t come. This phenomenon, known as having a word “on the tip of the tongue,” is both fascinating and frustrating. But what exactly is happening in the brain during these moments? Scientists have explored this question, uncovering some intriguing insights.

When a word is “on the tip of the tongue,” multiple regions of the brain spring into action, working to locate the missing term. Imagine a group of people frantically searching a library for a specific book. Similarly, the brain mobilizes specific areas to assist in this search. Three regions, in particular, play key roles: the anterior cingulate cortex, the prefrontal cortex and the insula.

The anterior cingulate cortex and the prefrontal cortex are part of a network responsible for cognitive control and perform complementary roles when a word is elusive. The anterior cingulate cortex acts like a supervisor, signaling that there’s a conflict: “I know this word, but I can’t retrieve it!” Meanwhile, the prefrontal cortex evaluates and verifies the information that surfaces during the search, ensuring that what is retrieved matches what you’re looking for. The insula, a deeper and less visible brain region, contributes to phonological retrieval–helping access the sounds that make up words.

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