With Man City now firmly ahead of Arsenal in the Premier League title race, following a 2-1 win over Leeds United on Saturday, Pep Guardiola's side continue their treble hunt against Champions League holders Real Madrid.
Kyle Walker is set to come into the side, with Manuel Akanji potentially replacing injured Dutch defender Nathan Ake at left-back, which means John Stones is set to move back into the centre of defence alongside Ruben Dias.
Ahead of the match, we carried out a simulation of the game on FIFA 23 and this is what happened...
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We predict that Real Madrid could line up in a 4-3-3 formation, with their line-up as follows: Courtois; Carvajal, Rudiger, Alaba, Camavinga; Valverde, Kroos, Modric; Rodrygo, Benzema, Vinicius Jnr.
We predict that City could set up in a 3-2-4-1 formation, with their line-up as follows: Ederson; Walker, Stones, Dias, Akanji; De Bruyne, Rodri, Gundogan; Bernardo Silva, Haaland, Grealish.
City were by far the better team in the early stages of the simulated game and Los Blancos looked vulnerable, with Erling Haaland's off-the-ball runs causing the home side real problems. And that's exactly how the visitors' first goal came about, with a run from Haaland leaving acres of space for De Bruyne to move in to.
Ilkay Gundogan found the Belgian with an intelligent pass, and the midfielder took a touch before rolling a finish under Thibaut Courtois to make it 1-0 on 22 minutes. City continued to dominate the ball but Madrid held firm to stay in the game, and began to look dangerous on the counter attack.
In the second half, City were doing everything they could to slow the game down, keeping the ball and moving Madrid from side to side. But Guardiola's side looked panicked every time Vinicius Jnr got the ball on the left, with the Brazilian clearly a huge threat on the break. But he didn't really make any inroads until being moved to the right temporarily, and free from Kyle Walker's searing pace, the Brazilian made it 1-1 on the counter.
Karim Benzema received the ball on the halfway line before turning and setting the forward away, who cut inside and produced a stunning finish with the outside of his right foot to level the game on the night.
Madrid finished the stronger and had chances to grab a winner, but Ederson was in fine form to deny the lines of Ernesto Valverde and Toni Kroos, as City held on to claim a 1-1 draw away from home.
FIFA 23 predicted final score: Real Madrid 1-1 Man City
FIFA 23 predicts that City have the quality to control possession and dominate, even at Santiago Bernabéu, with the visitors predicted to start strongly and take the lead through De Bruyne. But, this simulation also suggests that Carlo Ancelotti's side are a huge threat on the break, and will have to be defensively sound to deny the likes of Vinicius Jnr, Benzema and Rodrygo.