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WEKU
WEKU
Jon Hamilton

These LSD-based drugs seem to help mice with anxiety and depression — without the trip

LSD blotter tabs sit on top of a US quarter coin. A drug based off of psychedelic LSD appears to relieve depression and anxiety in mice, but without the hallucinogenic side effects. (PAUL J. RICHARDS/AFP via Getty Images)

Drugs like magic mushrooms and LSD can act as powerful and long-lasting antidepressants. But they also tend to produce mind-bending side-effects that limit their use.

Now, scientists report in the journal Nature that they have created drugs based on LSD that seem to relieve anxiety and depression – in mice – without inducing the usual hallucinations.

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