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The Guardian - UK
The Guardian - UK
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Devi Sridhar

The WHO learned to love ‘anti-obesity’ jabs in 2025. I don’t fully agree, but I get it

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If there has been a hot topic in health in 2025, it’s definitely been GLP-1s, colloquially referred to as “anti-obesity” jabs. These medications, taken weekly as an injection into the abdomen, result in significant weight loss and, despite being developed to manage type 2 diabetes in those with metabolic disorders, have become mainstream in many countries as a treatment for obesity. Clinicians rave about the health outcomes in patients taking the medication, with study after study emerging on the health benefits of the associated weight loss in those who are obese. Celebrity endorsements, online sales and off-label use have seen them widely used by people of all ages and sizes who want to drop weight.

For the public health community, it’s an odd moment. For years, we’ve advocated for government action on obesity – not through new drugs, but by taking nutrition and food systems seriously. We’ve highlighted the need for government action on making nutritious food affordable, regulating ultra-processed foods, bringing in sugar taxes and banning advertising of unhealthy products to young people, alongside encouraging an increase in physical activity. The solutions are simple: get people to eat more nutritious food and move. The challenge has been implementation, especially in deprived areas.

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