
When landing on the surface of the Moon, astronauts can become spatially disoriented, which is when they lose sense of their orientation – they might not be able to tell which way is up. This disorientation can lead to fatal accidents.
Even on Earth, between 1993 and 2013, spatial disorientation led to the loss of 65 aircraft, US$2.32 billion of damages and 101 deaths in the U.S.