Robin Le Normand makes his debut for Spain tonight after being named in the starting line-up to face Italy in the Nations League semi-finals.
Luis de la Fuente has picked the French-born defender following his declaration of allegiance to La Roja last month.
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Yeremy Pino also gets the nod in the attack opposite Leeds winger Rodrigo Moreno.
Sergio Busquets has retired, meaning Manchester City treble-winner Rodri starts alongside regular partner Mikel Merino with Pedri ruled out through injury.
The Italians, meanwhile, are striving towards getting back to a World Cup after missing the last two. Although Roberto Mancini has won the Euros, the Azzurri remain a shadow of themselves on the world stage.
Argentine-born Mateo Retegui is only on the bench after two goals in his first two international appearances. Ciro Immobile gets the nod ahead of him in a 5-3-2 formation.
Spain XI: Simon; Navas, Le Normand, Laporte, Alba; Moreno, Rodri; Rodrigo, Gavi, Pino; Morata.
Italy XI: Donnarumma; Di Lorenzo, Bonucci, Acerbi, Toloi, Spinazzola; Frattesi, Barella, Jorginho; Immobile, Zaniolo.