Guatemalan authorities say the Sinaloa Cartel, with support from local gangs, controls most of the clandestine drug laboratories in the country that produce synthetic drugs such as fentanyl and methamphetamine.
According to the National Civil Police (PNC), 27 so-called "narco labs" were dismantled in 2024. Of those, 19 were directly linked to the Sinaloa Cartel, and most were operated by the Huistas, one of Guatemala's most powerful drug trafficking groups.
