There were 20 confirmed cases of scarlet fever in Nottinghamshire in the last full week of November - with 124 reported in the East Midlands. Nottingham had six cases, while Derby had two.
In total, 861 cases of scarlet fever were reported throughout England and Wales. Eight cases of the more serious invasive Group A Strep - also known as iGAS - were noted across the UK during the same time frame.
Parents have been warned to be on the lookout for symptoms of scarlet fever, which is passed on by physical contact or through droplets from sneezing or coughing. In the vast majority of cases, children will make a full recovery after a mild illness.