Robin Veldman has left Queen's Park just hours after the club's defeat to Inverness in the Scottish Championship.
The Spiders have not won a league match since August and currently sit eighth in the division.
Veldman joined Queens Park in June after Owen Coyle's departure, signing a three-year deal.
A club statement read: "Queen's Park would advise that head coach Robin Veldman has left the club following this afternoon's match with Inverness Caledonian Thistle.
"Further information will be issued by the club in the coming days."
It comes after director of football Marijn Beuker also left, joining Ajax last month.
He had originally signed a 10-year deal with Queen's Park.
Meanwhile, Philippe Clement refused to criticise referee Kevin Clancy following Jose Cifuentes' red card against Dundee today.
The Ecuadorian midfielder was sent off following a VAR check after he could Dundee striker Amadou Bakayoko.
The former LAFC player was initially booked over the incident, however, after the intervention of VAR, Kevin Clancy opted to upgrade his decision to a red. Cifuentes did appear to catch the Dundee attacker high on the shin.
While Clement showed no anger over that decision, the Belgian did admit he was frustrated with Clancy over Todd Cantwell's disallowed goal during the first half. It was pulled back for a foul in the build-up, which meant the score stayed at 3-1.
"I never speak about a referee's performance because they make mistakes," Clement told BBC Sportsound. "We are on the training pitch every day to be our own referees, so are my assistants, so you cannot see everything.
"With the disallowed goal, I did not understand why the whistle was blown that fast. There was a clear view, so there was no foul, so it's better to let the play go on and then if there is a foul VAR can always come back to that. "
