Researchers have built the most detailed molecular map yet of how pancreatic tissue changes on its way to becoming cancer, and found that the reprogramming starts in ducts that still look entirely normal under a microscope.
The study, featured on the cover of Cancer Discovery and highlighted this week by the editors of the American Association for Cancer Research's journals, applied a technique called Deep Visual Proteomics to tissue spanning the full progression from healthy duct to invasive carcinoma.
