California: According to a study conducted at UCLA, a protein known as CEACAM1 helps shield the liver from damage during the transplantation process, which may enhance the success of the procedure. However, the characteristics that control this protective attribute are still unknown.A research team has discovered the molecular mechanisms underlying this protection and demonstrated how to increase CEACAM1's protectiveness through alternative gene splicing and molecular tools, thereby minimising organ damage and ultimately enhancing post-transplant outcomes. The results of this new study were published online in Science Translational Medicine.
