The Premier League makes a welcome return this weekend as all 20 top flight sides prepare for action following the two-week international break.
While many players were competing in the final round of UEFA Nations League group fixtures, others were simply stepping up preparations ahead of November’s 2022 FIFA World Cup, but that has come at a price for a number of clubs and their first team stars.
With the help of PremierInjuries.com, Mirror Football brings you a full round-up on the current state of play for every single Premier League club and which players could be set to miss out on the next round of fixtures through injury.
Information correct at time of writing
Arsenal
Injured/absent: Mohamed Elneny (thigh), Emile Smith Rowe (groin)
Doubtful: Thomas Partey (knee), Kieran Tierney (head), Oleksandr Zinchenko (calf), Cedric Soares (knock), Reiss Nelson (thigh)
Aston Villa
Injured/absent: Boubakar Kamara (knee), Lucas Digne (ankle), Diego Carlos (calf)
Doubtful: Matty Cash (hamstring)
Bournemouth
Injured/absent: Ryan Fredericks, Lloyd Kelly (knee), David Brooks (thigh)
Doubtful: Ben Pearson (knee), Joe Rothwell (thigh)
Brentford
Injured/absent: None
Doubtful: Keane Lewis-Potter, Christian Norgaard (Achilles), Ethan Pinnock (knee)
Brighton
Injured/absent: Jakub Moder (knee)
Doubtful: Enock Mwepu (illness), Adam Lallana (calf)
Chelsea
How much have Chelsea missed N'Golo Kante this season? Let us know your thoughts in the comments section below.
Injured/absent: None
Doubtful: Edouard Mendy (knee), N’Golo Kante (thigh)
Crystal Palace
Injured/absent: James Tomkins (calf), Nathan Ferguson (ankle)
Doubtful: Jack Butland (wrist), James McCarthur (groin)
Everton
Injured/absent: Mason Holgate (knee), Yerry Mina (ankle), Nathan Patterson (ankle), Andros Townsend (knee), Ben Godfrey (leg)
Doubtful: Jordan Pickford (thigh), Dominic Calvert-Lewin (groin)
Fulham
Injured/absent: Joao Palhina (suspended), Harry Wilson (knee), Manor Solomon (knee)
Doubtful: Aleksandr Mitrovic (ankle), Antonee Robinson (ankle)
Leeds
Injured/absent: Stuart Dallas (thigh)
Doubtful: Rodrigo (shoulder)
Leicester
Injured/absent: Ricardo Pereira (Achilles), Ryan Bertrand (knee)
Doubtful: Patson Daka (virus), Wilfred Ndidi (hamstring)
Liverpool
Injured/absent: Naby Keita (thigh), Alex Oxlade-Chamberlain (thigh), Curtis Jones (shin), Calvin Ramsay (lower back)
Doubtful: Ibrahima Konate (knee), Andrew Robertson (knee), Caoimhin Kelleher (groin)
Manchester City
Injured/absent: John Stones (thigh), Kalvin Phillips (shoulder)
Doubtful: Aymeric Laporte (knee)
Manchester United
Injured/absent: Harry Maguire (hamstring), Martin Dubravka (muscular), Anthony Martial (calf), Brandon Williams
Doubtful: Marcus Rashford (thigh), Donny van de Beek (knock)
Newcastle
Injured/absent: Alexander Isak (leg), Chris Wood (rib), Emil Krafth (knee), Jonjo Shelvey (thigh), Karl Darlow (ankle)
Doubtful: Allan Saint-Maximin (thigh), Callum Wilson (thigh), Bruno Guimaraes (thigh), Elliott Anderson (knock)
Nottingham Forest
Injured/absent: Moussa Niakhate (thigh), Scott McKenna (knee)
Doubtful: Orel Mangala (thigh), Omar Richards (calf), Joe Worrall (broken nose), Morgan Gibbs-White (knock), Emmanuel Dennis (knock)
Southampton
Injured/absent: Valentino Livramento (knee), Romeo Lavia
Doubtful: None
Tottenham
Injured/absent: None
Doubtful: Dejan Kulusevski (muscular), Hugo Lloris (thigh), Ben Davies (knee), Lucas Moura (calf)
West Ham
Injured/absent: Nayef Aguerd (ankle)
Doubtful: Ben Johnson (thigh)
Wolves
Injured/absent: Nathan Collins (suspended), Raul Jimiinez (groin), Sasa Kalajdzic (knee), Chiquinho (knee)
Doubtful: Diego Costa