Week 15 of the NFL season gets underway with a Thursday night date from Levi’s Stadium between the San Francisco 49ers (6-7) and Los Angeles Rams (7-6).
In a key late-season NFC West showdown, this contest essentially serves as its own playoff game of sorts for the 49ers. Already trailing Seattle (8-5) by two games in the division standings, San Francisco simply doesn’t have enough real estate left in the season to mount a charge for the division title if they drop Thursday night’s battle against the Rams.
In the two teams’ first meeting of the season, San Francisco watched a pair of two-touchdown leads evaporate in a 27-24 loss on Sept. 22. Rams kicker Joshua Karty connected on the game-winning, 37-yard field goal with just two ticks remaining to down the 49ers.
San Francisco snapped a three-game losing streak in Week 14 with a rousing performance in the 49ers’ 38-13 blowout of the Chicago Bears. Meanwhile, Los Angeles toppled Buffalo, 44-42, in a shootout from SoFi Stadium.
As the scene between these two shifts to Santa Clara, Calif., here’s a look at the teams’ respective injury reports and the latest odds, including the point spread, money line numbers and the current over-under point total.
Plus, a prediction on how this latest installment of 49ers-Rams unfolds.
49ers vs. Rams game odds:
All NFL Odds via BetMGM:
- Point spread: 49ers -3
- Money line: 49ers -150 / Rams +125
- Over-under: 48.5
49ers vs. Rams injury updates:
- 49ers OL Ben Bartch – OUT (ankle)
- 49ers LT Trent Williams – OUT (ankle)
- 49ers S Malik Mustapha – OUT (chest, shoulder)
- 49ers DL Nick Bosa – Questionable (hip, oblique)
- 49ers RB Isaac Guerendo – Questionable (foot)
- 49ers LB Dre Greenlaw – Questionable (Achilles)
- 49ers DL Khalil Davis – Questionable (knee)
- Rams CB Cobie Durant – OUT (chest)
- Rams TE Tyler Higbee – OUT (knee)
- Rams WR Demarcus Robinson – Questionable (shoulder)
- Rams WR Jordan Whittington – Questionable (shoulder)
- Rams TE Davis Allen – Questionable (shoulder)
- Rams DE Tyler Davis – Questionable (calf)
- Rams OL Beaux Limmer – Questionable (knee)
- Rams OL Alaric Jackson – Questionable (knee)
49ers vs. Rams prediction, pick
Prediction: 49ers 30, Rams 27
Facing another must-win situation on a short week, 49ers quarterback Brock Purdy authors another strong performance against a Rams secondary that can be picked apart.
On a week where tweets got deleted, it’s wide receiver Deebo Samuel that goes off for the 49ers in a win that signals that San Francisco isn’t quite done yet in 2024.
49ers vs. Rams channel, start time, streaming:
The 49ers vs. Rams game starts at 5:15 p.m. PT and can be seen on Amazon Prime Video.
Get more betting analysis and predictions at Sportsbook Wire.
