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LiveScience
LiveScience
Sascha Pare

Nearly 150 genes involved in cartilage development may control human height, study suggests

Cells that make up the cartilage at the end of children's and teens' bones determine their future length and shape, which, in turn, affect height.  (Image credit: Marko Geber via Getty Images)

Scientists have pinpointed 145 potential "height genes" in cells that make up the cartilage at the ends of children's bones and affect how tall they grow.

These cartilage cells, known as chondrocytes, multiply and mature in areas of tissue called growth plates, which sit near the ends of long bones in children and teens and determine each bone's future length and shape. When a person's growth is complete, these cartilaginous growth plates "close" and are replaced by hard bone. Scientists already knew that chondrocytes play a role in bone growth and human height, but narrowing down which genes control the cells' growth — and, thus, our statures — has proved difficult.

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