
Microsoft has just upgraded its Azure cloud platform with Nvidia's Blackwell Ultra, deploying what it calls the world's first large-scale GB300 NVL72 supercomputing cluster. This cluster includes several racks housing exactly 4,608 GB300 GPUs connected by NVLink 5 switch fabric, which is then interconnected via Nvidia’s Quantum-X800 InfiniBand networking fabric across the entire cluster. This allows a single NVL72 rack to have a total memory bandwidth of 130 TB/s, with each rack providing 800 Gb/s of interconnect bandwidth per GPU.
The world's first large-scale @nvidia GB300 NVL72 supercomputing cluster for AI workloads is now live on Microsoft Azure. The deployment connects 4,600+ NVIDIA Blackwell Ultra GPUs using next-gen InfiniBand network—built to train and deploy advanced AI models faster than… pic.twitter.com/CmmDtcrlwnOctober 9, 2025