Raphael Varane, Scott McTominay and Fred are all set to miss Manchester United's Premier League fixture at Liverpool.
The trio missed the win over Norwich on Saturday. Varane and McTominay (foot) have been sidelined for the last two games and Fred has not recovered from a hip flexor problem he sustained at Everton.
Edinson Cavani and Luke Shaw are possibly out for the rest of the season and the depleted state of the midfield could force interim manager Ralf Rangnick to start Nemanja Matic and Paul Pogba.
