A sprawling 400-house development in Kilwinning was given the go ahead by North Ayrshire Council's planning committee on Wednesday after concerns over traffic issues were allayed.
The Persimmon Homes development is at West Byrehill, which had been identified as an employment area by Irvine Development Corporation in the 1970s but failed to take off.
It was looked at in 2013 as an industrial development site but was considered unsuitable.