Marcelo Bielsa has made two changes to the Leeds United side that defeated West Ham 3-2 at the London Stadium last weekend.
Diego Llorente and Rodrigo Moreno are the two players to come into the Whites' starting XI, with Junior Firpo and Adam Forshaw both dropping out due to hamstring injuries.
That means Daniel James is again set to start in a central striker role, despite the return of both Joe Gelhardt and Tyler Roberts to the squad.