Omonia Nicosia seemed to clear the danger from Christian Eriksen's free-kick on Thursday night. The ball travelled to Jadon Sancho on the edge of the box and he decided to turn back before passing to Tyrell Malacia, who was the last man at the halfway line.
Malacia's touch was heavy, he crumbled under pressure and conceded possession to Omonia for a counter-attack. Malacia, Eriksen, Lisandro Martinez, Diogo Dalot and Casemiro sprinted back in an effort to make amends but their running would be in vain.
Omonia might only be fourth in the Cypriot first division, but few sides competing in European competition would waste such an opportunity, which meant David de Gea was helpless as 32-year-old Karim Ansarifard fired into the roof of the net.