Prince Harry has revealed he "felt different" to the rest of the Royal Family throughout his life and "strange being in this container".
He was joined by Dr Gabor Maté for a live Q+A session to promote his memoir, Spare, where he said his mother, Princess Diana, felt similarly.
"I certainly have felt throughout my life, my younger years, I always felt slightly different to the rest of my family," he said.
"I felt strange being in this container. And I know that my mum felt the same."
It comes after Duke of Sussex earlier told how he has "never looked for sympathy" and isn't a victim.
He said: "I certainly don’t see myself as a victim", adding that he wanted to help others by "sharing my story".
"And I have never looked for sympathy in this, for me.
"It's for me experiences that I've had throughout my childhood, throughout my life, throughout my 38 years, albeit relatively short. I'm not looking forward to becoming 40, that's for sure."
Harry told an audience, who forked out just under £20 for tickets, he wants to help others by sharing his story.
He added: "I thought if I went to therapy that it would cure me and that I would lose whatever I had left, whatever I had managed to hold on to of my mother.
"I didn't lose that, it was the opposite.
"I turned what i thought was supposed to be sadness to try to prove to her that I missed her into realising that she really just wanted me to be happy and that was a huge weight off my chest."
During the conversation, Harry spoke about the tragedy of losing his mum, Diana, and revealed he feared losing the memory of her and has taken part in counselling sessions about his childhood trauma.
He admitted he wished he had begun counselling sooner and suddenly felt like he "learnt a new language" once he started going regularly.
Although he added that once he began understanding the trauma and living a "more authentic life and being a better dad" he realised he was becoming more distant from the Royal Family.
Harry’s late mother, Diana, Princess of Wales, died in a car crash in Paris in 1997 when the duke was just 12 years old.
In Spare, which was written with the help of a ghost writer, Harry described how difficult it was to deal with her death and he described the princess as his “guardian angel” and said she is with him “all the time”.
Harry also hit out at his family, accusing his brother Prince William of physically attacking him and King Charles of refusing to hug him after Diana died.
The Duke of Sussex’s controversial memoir has become the fastest-selling non-fiction book in the UK since records began in 1998.
During the event the Prince answered pre-submitted questions from the audience which were read out by the moderator.
Tickets cost £17 plus a £2.12 fee for UK customers, which included a copy of the book.
Harry hasn't revealed how much cash he made from the book, however he has given some of the profits to charity.