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Alison Clare, Senior Research Associate, Translational Health Sciences and Ophthalmology, University of Bristol

Gene therapy can be less effective in women – and my research in mice brings us one step closer to understanding why

Some gene therapies may be less effective in women. crystal light/ Shutterstock

Gene therapies hold immense promise for treating sight loss. These therapies use a modified, harmless virus to deliver therapeutic genes directly to diseased cells, helping them to function normally again.

But numerous clinical trials have found that gene therapy causes serious side-effects in some patients because their immune system recognises the virus and attacks it.

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