With the transfer window very much behind Spurs now, Antonio Conte has a relatively new look squad who are ready to challenge for a top four place.
The deadline day signings of Dejan Kulusevski and Rodrigo Bentancur strengthened the Lilywhites, who currently occupy seventh position in the Premier League.
But there are expected to be plenty of twists and turns before the season comes to an end, and with Spurs still set to play a number of their top four rivals, Conte has his work cut out to ensure Tottenham qualify for the Champions League.