Nausea and stomach upset are so routine on GLP-1 drugs that most patients and prescribers treat them as background noise. That expectation is exactly what made one Saudi case worth publishing.
A 57-year-old woman with type 2 diabetes had been on semaglutide when she developed epigastric pain, loss of appetite, and unintended weight loss that dragged on for four months. Her bloodwork showed marked peripheral eosinophilia, and endoscopic biopsies of her stomach and duodenum revealed extensive eosinophilic infiltration of the lamina propria, confirming eosinophilic gastroenteritis.
