What would happen if you gave up your morning coffee for two weeks? Would you sleep better, feel less anxious, or spend your mornings battling headaches and exhaustion?
Scientists recently explored that question, and their findings suggest that quitting coffee can affect much more than your energy levels. In a 2026 study published in Nature Communications, researchers examined what happened when habitual coffee drinkers stopped consuming coffee for 14 days before reintroducing either caffeinated or decaffeinated coffee. The results revealed changes in fatigue, mood, cognitive performance, and the gut microbiome, the collection of microorganisms living in the digestive system.
